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A Novel Metamaterial-Inspired RF-coil for Preclinical Dual-Nuclei MRI

机译:一种用于临床前双核mRI的新型超材料激励射频线圈

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摘要

In this paper we propose, design and test a new dual-nuclei RF-coil inspiredby wire metamaterial structures. The coil operates due to resonant excitationof hybridized eigenmodes in multimode flat periodic structures comprisingseveral coupled thin metal strips. It was shown that the field distribution ofthe coil (i.e. penetration depth) can be controlled independently at twodifferent Larmor frequencies by selecting a proper eigenmode in each of twomutually orthogonal periodic structures. The proposed coil requires no lumpedcapacitors for tuning and matching. In order to demonstrate the performance ofthe new design, an experimental preclinical coil for $^{19}$F/$^{1}$H imagingof small animals at 7.05T was engineered and tested on a homogeneous liquidphantom and in-vivo. The presented results demonstrate that the coil was welltuned and matched simultaneously at two Larmor frequencies and capable of imageacquisition with both the nuclei reaching large homogeneity area along with asufficient signal-to-noise ratio. In an in-vivo experiment it has been shownthat without retuning the setup it was possible to obtain anatomical $^{1}$Himages of a mouse under anesthesia consecutively with $^{19}$F images of a tinytube filled with a fluorine-containing liquid and attached to the body of themouse.
机译:在本文中,我们提出,设计和测试了受线超材料结构启发的新型双核RF线圈。线圈由于包含多个耦合的薄金属条的多模平坦周期结构中的混合本征模的共振激发而工作。已经表明,通过在两个相互正交的周期结构的每一个中选择适当的本征模,可以在两个不同的拉莫尔频率上独立地控制线圈的场分布(即,穿透深度)。提出的线圈不需要集总电容器来进行调谐和匹配。为了证明新设计的性能,在7.05T对小型动物进行$ ^ {19} $ F / $ ^ {1} $ H成像的实验性临床前线圈进行了工程设计,并在均质的幻影和体内进行了测试。提出的结果表明,该线圈在两个拉莫尔频率下均进行了良好的调谐和匹配,并且能够进行图像采集,两个原子核均达到大的均匀区域,并且信噪比不足。在体内实验中显示,无需重新调整设置,就有可能连续获取麻醉下小鼠的解剖学$ ^ {1} $ H图像,并依次获得填充有氟的细管的$ ^ {19} $ F图像。装有液体并附着在老鼠身上。

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